SCHEMBL614178

SCHEMBL614178

[SiH3]OC(CCCOCC1CO1)(CCCOCC1CO1)CCCOCC1CO1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.53
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPK1 P28482 1/20 0.41
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL613049 0.98 TSHR (0.64) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL611565 0.90 SMN1; SMN2 (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL614617 0.90 SMN1; SMN2 (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL5268219 0.89 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL614628 0.86 TSHR (0.58) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL614218 0.82 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL125940 0.82 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1223731 0.82 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL8441407 0.80 TSHR (0.48) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL153464 0.79 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256238-B2 Modified block copolymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-08-14 US claimed
EP-1199313-B1 Diene polymers and copolymers having an alkoxysilane group BRIDGESTONE CORP (JP) 2005-08-24 EP claimed
EP-0620255-B1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD (KR) 2002-02-27 EP claimed
US-5917075-A Hydrolyzable and polymerizable silanes FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG, E.V. (DE) 1999-06-29 US claimed
US-5674941-A CURABLE PROTECTIVE COATING FOR OPTICAL ARTICLES COMPRISING AN AMINE-CONTAINING SILANE AND AN ACRYLIC COPOLYMER HAVING PENDANT HYDROXY, EPOXY, AMINO AND/OR SILANE GROUPS; ANTIFOGGING AGENTS; ADHESION TO POLYCARBONATES; NONABRASIVE LUCKY LIMITED (KR) 1997-10-07 US claimed
EP-4269516-A1 COMPOSITION FOR HYBRID POLYMERS HAVING BARRIER FUNCTION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-11-01 EP disclosed
WO-2023008424-A1 RESIN COMPOSITION, METHOD FOR PRODUCING RESIN COMPOSITION, AND MOLDED BODY 旭化成株式会社 2023-02-02 WO disclosed
US-10072138-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD (JP) 2018-09-11 US disclosed
EP-1441887-B1 ANTI-ADHESIVELY COATED FORMING TOOLS MOMENTIVE PERFORMANCE MAT GMBH (DE) 2018-05-16 EP disclosed
US-20180022913-A1 Block Copolymer Composition, Molded Material, Resin Composition, and Molded Product ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-01-25 US disclosed
EP-3257896-A1 BLOCK COPOLYMER COMPOSITION, MOLDING MATERIAL, RESIN COMPOSITION, AND MOLDED ARTICLE Asahi Kasei Kabushiki Kaisha (JP) 2017-12-20 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
EP-0773231-A2 Diene polymers and copolymers having an alkoxysilane group Bridgestone Corporation (JP) 1997-05-14 EP disclosed
EP-0767179-A2 Method for producing a rubber composition Bridgestone Corporation (JP) 1997-04-09 EP disclosed
EP-0525392-B1 Hydrolysable and polymerisable silanes FRAUNHOFER GES FORSCHUNG (DE) 1996-08-21 EP disclosed
US-5508333-A NONCRACKING, WEAR RESISTANCE, HYSTERESIS-FREE; TIRES BRIDGESTONE CORPORATION (JP) 1996-04-16 US disclosed
EP-0694550-A2 Hydrolysable and polymerisable silanes FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1996-01-31 EP disclosed
EP-0661298-A2 Diene polymers and copolymers having an alkoxysilane group BRIDGESTONE CORPORATION (JP) 1995-07-05 EP disclosed
EP-0525392-A1 Hydrolysable and polymerisable silanes FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1993-02-03 EP disclosed
US-4642266-A SCRATCH RESISTANCE AND WEATHERABILITY NIPPON SHEET GLASS CO., LTD. (JP) 1987-02-10 US disclosed