Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314536 | 0.93 | F10 (0.40) | F10POLBLMNANCOA1NCOA3 | |
| SCHEMBL5270690 | 0.93 | POLB (0.40) | F10POLBLMNANCOA1NCOA3 | |
| SCHEMBL5264920 | 0.93 | F10 (0.44) | F10POLBLMNACYP1A2CYP3A4 | |
| SCHEMBL5266888 | 0.90 | F10 (0.47) | F10 | |
| SCHEMBL2766694 | 0.88 | F10 (0.47) | F10POLBLMNACYP1A2CYP3A4 | |
| SCHEMBL5266415 | 0.87 | F10 (0.41) | F10POLBLMNACYP1A2CYP3A4 | |
| SCHEMBL4506653 | 0.87 | F10 (0.57) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4492727 | 0.87 | F10 (0.57) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4491287 | 0.87 | F10 (0.57) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5266535 | 0.86 | LMNA (0.41) | POLBLMNANCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836198-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069946-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-07-06 | — | — | WO | disclosed |