Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266476 | 0.93 | F10 (0.46) | F10POLBLMNANCOA1NCOA3 | |
| SCHEMBL5270690 | 0.89 | POLB (0.40) | F10POLBLMNANCOA1NCOA3 | |
| SCHEMBL4503977 | 0.87 | F10 (0.49) | F10POLBLMNATP53 | |
| SCHEMBL5264920 | 0.85 | F10 (0.44) | F10POLBLMNANCOA1NCOA3 | |
| SCHEMBL5266888 | 0.83 | F10 (0.47) | F10 | |
| SCHEMBL5266535 | 0.82 | LMNA (0.41) | POLBLMNANCOA1NCOA3TP53 | |
| SCHEMBL5266875 | 0.82 | POLB (0.41) | F10POLBLMNANCOA1NCOA3 | |
| SCHEMBL2767390 | 0.82 | POLB (0.42) | POLBLMNANCOA1NCOA3TP53 | |
| SCHEMBL2766694 | 0.81 | F10 (0.47) | F10POLBLMNANCOA1NCOA3 | |
| SCHEMBL5266415 | 0.81 | F10 (0.41) | F10POLBLMNANCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836198-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069946-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-07-06 | — | — | WO | disclosed |