Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL5266577 | 1.00 | TSHR (0.52) | TSHRAPOBEC3AHTTAPOBEC3GKMT2A | |
| Hydroxyamine SCHEMBL5274861 | 0.91 | GAA (0.53) | KMT2AGAAALDH1A1CYP1A2POLB | |
| Hydroxyamine SCHEMBL5274854 | 0.91 | GAA (0.53) | KMT2AGAAALDH1A1CYP1A2POLB | |
| SCHEMBL3546824 | 0.87 | FKBP1A (0.55) | TSHRAPOBEC3AHTTAPOBEC3GKMT2A | |
| SCHEMBL3546826 | 0.87 | FKBP1A (0.55) | TSHRAPOBEC3AHTTAPOBEC3GKMT2A | |
| SCHEMBL3544922 | 0.86 | TSHR (0.49) | TSHRAPOBEC3AHTTAPOBEC3GKMT2A | |
| SCHEMBL3544921 | 0.86 | TSHR (0.49) | TSHRAPOBEC3AHTTAPOBEC3GKMT2A | |
| SCHEMBL11998537 | 0.81 | FKBP1A (0.56) | KMT2AGAAALDH1A1CYP1A2POLB | |
| SCHEMBL3554498 | 0.79 | ALDH1A1 (0.48) | TSHRAPOBEC3AHTTAPOBEC3GKMT2A | |
| SCHEMBL3554500 | 0.79 | ALDH1A1 (0.48) | TSHRAPOBEC3AHTTAPOBEC3GKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539744-A4 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARM INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1539744-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004007444-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | WO | disclosed |