Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181492 | 0.94 | THRB (0.54) | THRBLMNAMTNR1AMTNR1BMAOA | |
| SCHEMBL9854345 | 0.87 | TSHR (0.43) | THRBLMNAMTNR1AMTNR1BCYP2D6 | |
| SCHEMBL19770674 | 0.84 | AR (0.43) | LMNA | |
| SCHEMBL19770673 | 0.84 | AR (0.43) | LMNA | |
| SCHEMBL9915775 | 0.83 | THRB (0.43) | THRBLMNAMTNR1AMTNR1BMAPT | |
| SCHEMBL896674 | 0.82 | MTNR1A (0.53) | THRBLMNAMTNR1AMTNR1BMAOA | |
| SCHEMBL14173246 | 0.82 | ACACB (0.43) | THRBLMNACYP2D6MAPT | |
| SCHEMBL896831 | 0.82 | MTNR1A (0.53) | THRBLMNAMTNR1AMTNR1BMAOA | |
| SCHEMBL13554408 | 0.82 | MAPT (0.43) | THRBLMNACYP2D6MAPT | |
| SCHEMBL14173248 | 0.82 | ACACB (0.43) | THRBLMNACYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840654-B1 | Radiation-sensitive negative resin composition | JSR CORP (JP) | 2013-03-20 | — | — | EP | disclosed |
| US-20070231747-A1 | Radiation-sensitive negative resin composition | JSR CORPORATION (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1840654-A1 | Radiation-sensitive negative resin composition | JSR Corporation (JP) | 2007-10-03 | — | — | EP | disclosed |