Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 11/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955574 | 0.88 | CCNA2 (0.62) | HPGDRXFP1SMN1; SMN2GAAHDAC3 | |
| SCHEMBL5269651 | 0.84 | HPGD (0.52) | HPGDSMN1; SMN2CETPHDAC3HDAC1 | |
| SCHEMBL2799869 | 0.83 | HPGD (0.46) | HPGDSMN1; SMN2GAACETPHDAC3 | |
| SCHEMBL5265757 | 0.82 | SMN1; SMN2 (0.46) | HPGDSMN1; SMN2GAACETPHDAC3 | |
| SCHEMBL5269109 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2GAA | |
| SCHEMBL5267787 | 0.81 | NPC1 (0.44) | HPGDSMN1; SMN2GAACETPHDAC3 | |
| SCHEMBL5268520 | 0.81 | ALDH1A1 (0.47) | HPGDRXFP1SMN1; SMN2GAACETP | |
| SCHEMBL5272055 | 0.81 | EPHX2 (0.60) | SMN1; SMN2 | |
| SCHEMBL4292756 | 0.80 | NPC1 (0.44) | HPGDSMN1; SMN2CETPHDAC3HDAC1 | |
| SCHEMBL15528295 | 0.79 | RXFP1 (0.75) | HPGDRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |