Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.40 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.40 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.40 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116740 | 0.83 | HRH3 (0.48) | HRH3PTGS2KCNH2 | |
| SCHEMBL2114205 | 0.81 | HRH3 (0.52) | HRH3KCNH2 | |
| SCHEMBL2114120 | 0.81 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL2019376 | 0.75 | HRH1 (0.70) | HRH3HRH1ROCK1ROCK2PRKACA | |
| SCHEMBL14431595 | 0.71 | HRH1 (0.59) | HRH3HRH1 | |
| SCHEMBL12975670 | 0.71 | QDPR (0.41) | PTGS2ALOX5PTGS1 | |
| SCHEMBL2115508 | 0.70 | HRH3 (0.63) | HRH3HRH1ROCK1ROCK2PRKACA | |
| SCHEMBL2117437 | 0.70 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL18322912 | 0.69 | HRH3 (0.44) | HRH3HRH1ROCK1TLR9TLR8 | |
| SCHEMBL5204218 | 0.69 | HRH1 (0.79) | HRH3HRH1ROCK1KHKGRK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1820797-A1 | SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |