Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RPA1 | P27694 | 8/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268930 | 0.87 | SMN1; SMN2 (0.39) | ALDH1A1RPA1SMN1; SMN2KDM5AKDM4C | |
| SCHEMBL5269052 | 0.87 | RPA1 (0.44) | ALDH1A1RPA1PPP1CASMN1; SMN2L3MBTL1 | |
| SCHEMBL5267609 | 0.86 | RPA1 (0.45) | ALDH1A1RPA1PPP1CASMN1; SMN2MAPT | |
| SCHEMBL5270498 | 0.82 | CHRNA7 (0.42) | SMN1; SMN2KDM5AMAPTHTTMEN1 | |
| SCHEMBL5268336 | 0.81 | CHRNA7 (0.39) | SMN1; SMN2KDM5AMAPTHTTMEN1 | |
| SCHEMBL5273268 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1RPA1PPP1CASMN1; SMN2L3MBTL1 | |
| SCHEMBL5267292 | 0.77 | KDM5A (0.34) | KDM5A | |
| SCHEMBL5272583 | 0.75 | SMN1; SMN2 (0.42) | RPA1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL14529314 | 0.74 | ALDH1A1 (0.43) | ALDH1A1RPA1PPP1CASMN1; SMN2MAPT | |
| SCHEMBL5527496 | 0.74 | MALT1 (0.43) | ALDH1A1RPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254881-A1 | Pyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20070254881-A1 | Pyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20070254881-A1 | Pyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| EP-1785418-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254881-A1 | Pyrazole Derivative | PTGER1, PTGS1, PTGER2 | ALDH1A1 111/4885RPA1 1150/4885PPP1CA 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.