Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272583 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2PTGS2MEN1KMT2AJMJD6 | |
| SCHEMBL5267424 | 0.87 | ALDH1A1 (0.44) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5269089 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2PTGS2JMJD6FAAHMGLL | |
| SCHEMBL5270498 | 0.79 | CHRNA7 (0.42) | SMN1; SMN2PTGS2MEN1KMT2AHPGD | |
| SCHEMBL5267609 | 0.79 | RPA1 (0.45) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5268336 | 0.78 | CHRNA7 (0.39) | SMN1; SMN2PTGS2MEN1KMT2AHPGD | |
| SCHEMBL5527496 | 0.76 | MALT1 (0.43) | ALDH1A1RPA1 | |
| SCHEMBL5269052 | 0.75 | RPA1 (0.44) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5270243 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2PTGS2ALDH1A1KDM5AKDM4C | |
| SCHEMBL5267292 | 0.74 | KDM5A (0.34) | HPGDMGLLKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254881-A1 | Pyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| EP-1785418-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254881-A1 | Pyrazole Derivative | PTGER1, PTGS1, PTGER2 | SMN1; SMN2 3490/4885PTGS2 4/4885MEN1 3587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.