SCHEMBL5267572

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5271409	0.87	TP53 (0.48)	RPA1ALDH1A1GAA
	SCHEMBL5267172	0.86	PPP1CA (0.50)	RPA1MDM2MCL1BCL2SMN1; SMN2
	SCHEMBL5524318	0.86	MDM2 (0.59)	RPA1MDM2MCL1BCL2
	SCHEMBL5527873	0.86	CNR1 (0.44)	RPA1MARS1SMN1; SMN2KDM4EALDH1A1
	SCHEMBL27668640	0.86	RPA1 (0.42)	RPA1MARS1MDM2MCL1BCL2
	SCHEMBL27648473	0.85	RPA1 (0.46)	RPA1MDM2MCL1BCL2SMN1; SMN2
	SCHEMBL5268213	0.83	SMN1; SMN2 (0.46)	RPA1MDM2MCL1BCL2SMN1; SMN2
	SCHEMBL5270171	0.83	PTGS2 (0.55)	SMN1; SMN2
	SCHEMBL5267891	0.82	RPA1 (0.50)	RPA1MDM2MCL1BCL2SMN1; SMN2
	SCHEMBL5272729	0.82	MGLL (0.47)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.