Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 19/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 19/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 19/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166129 | 0.84 | ADRA1D (0.50) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL526176 | 0.84 | MAPT (0.48) | ADRA1DADRA1AADRA1BNPC1MAPT | |
| SCHEMBL525720 | 0.81 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL10182835 | 0.75 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL10064583 | 0.73 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL526254 | 0.72 | NOTUM (0.38) | ADRA1DADRA1AADRA1BNPC1MAPT | |
| SCHEMBL12505326 | 0.72 | MAPT (0.38) | ADRA1DADRA1AADRA1BNPC1MAPT | |
| SCHEMBL7906301 | 0.71 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL19730570 | 0.71 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL15061753 | 0.69 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014186-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN AND ITS NOVEL INTERMEDIATES | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |