Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270824 | 0.93 | PTPN1 (0.37) | PPARDMEN1KMT2APOLBPTPN1 | |
| SCHEMBL5506161 | 0.91 | BRD4 (0.38) | PPARDMEN1KMT2APOLBMAPT | |
| SCHEMBL5337927 | 0.87 | HTR2A (0.34) | PPARDMEN1KMT2APOLBPTPN1 | |
| SCHEMBL5517754 | 0.86 | POLB (0.36) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL5503574 | 0.85 | MEN1 (0.39) | PPARDMEN1KMT2APOLBPTPN1 | |
| SCHEMBL5510893 | 0.84 | PPARD (0.39) | PPARDMEN1KMT2APOLBPTPN1 | |
| SCHEMBL5266914 | 0.83 | MAPT (0.41) | PPARDMEN1KMT2APOLBPTPN1 | |
| SCHEMBL5271428 | 0.83 | MAPT (0.41) | PPARDMEN1KMT2APOLBPTPN1 | |
| SCHEMBL5506207 | 0.83 | TP53 (0.41) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL5516043 | 0.83 | POLB (0.43) | MEN1KMT2APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838669-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006077365-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |