Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270824 | 0.92 | PTPN1 (0.37) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL5516043 | 0.91 | POLB (0.43) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL5267628 | 0.86 | PPARD (0.39) | POLBMAPTMEN1KMT2ATDP1 | |
| SCHEMBL5515208 | 0.85 | MAPT (0.38) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL5506461 | 0.84 | ALOX5 (0.40) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL5503574 | 0.84 | MEN1 (0.39) | POLBMAPTMEN1KMT2ATDP1 | |
| SCHEMBL5266671 | 0.83 | POLB (0.41) | POLBL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL5510893 | 0.83 | PPARD (0.39) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5506207 | 0.82 | TP53 (0.41) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5508283 | 0.82 | TP53 (0.42) | POLBMAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |