Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270824 | 0.92 | PTPN1 (0.37) | MEN1KMT2APOLBPTPN1MAPT | |
| SCHEMBL5506207 | 0.92 | TP53 (0.41) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL5510893 | 0.91 | PPARD (0.39) | MEN1KMT2APOLBPTPN1MAPT | |
| SCHEMBL5503249 | 0.90 | KDM4E (0.37) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL5508283 | 0.90 | TP53 (0.42) | MEN1KMT2APOLBPTPN1MAPT | |
| SCHEMBL5509130 | 0.88 | DHFR (0.38) | MEN1KMT2APOLBPTPN1MAPT | |
| SCHEMBL5524203 | 0.85 | MEN1 (0.41) | MEN1KMT2APOLBFFAR1MAPT | |
| SCHEMBL5267628 | 0.85 | PPARD (0.39) | MEN1KMT2APOLBPTPN1FFAR1 | |
| SCHEMBL5517754 | 0.84 | POLB (0.36) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL5508776 | 0.84 | POLB (0.41) | MEN1KMT2APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |