Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 18/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105134 | 0.91 | P2RY12 (0.81) | P2RY12CYP3A4CYP2C9 | |
| SCHEMBL5592539 | 0.89 | P2RY12 (0.65) | P2RY12CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL29258649 | 0.86 | P2RY12 (0.81) | P2RY12CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL5264696 | 0.85 | P2RY12 (0.65) | P2RY12CYP3A4CYP2C9 | |
| SCHEMBL29258458 | 0.82 | P2RY12 (0.74) | P2RY12CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL4109942 | 0.81 | P2RY12 (0.81) | P2RY12CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL4098259 | 0.80 | P2RY12 (1.00) | P2RY12CYP3A4CYP2C9 | |
| SCHEMBL4105892 | 0.80 | P2RY12 (0.80) | P2RY12CYP3A4CYP2C9 | |
| SCHEMBL5315088 | 0.78 | P2RY12 (0.69) | P2RY12CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL5599353 | 0.78 | P2RY12 (0.82) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836189-A1 | NOVEL PYRIDINE COMPOUNDS | AstraZeneca AB (SE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006073361-A9 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |
| WO-2006073361-A1 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-07-13 | — | — | WO | disclosed |