Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269177 | 0.92 | RAB9A (0.56) | RAB9ANPC1GAAKDM4EHSD17B10 | |
| SCHEMBL5272812 | 0.91 | RAB9A (0.56) | RAB9ANPC1GAAKDM4EHSD17B10 | |
| SCHEMBL5265198 | 0.91 | RAB9A (0.55) | RAB9ANPC1GAAKDM4EHSD17B10 | |
| SCHEMBL5269482 | 0.90 | POLB (0.54) | RAB9ANPC1GAAMAPTPOLB | |
| SCHEMBL5267731 | 0.90 | RAB9A (0.54) | RAB9ANPC1MAPTPOLBTDP1 | |
| SCHEMBL5266973 | 0.90 | RAB9A (0.54) | RAB9ANPC1MAPTPOLBTDP1 | |
| SCHEMBL5267412 | 0.90 | RAB9A (0.54) | RAB9ANPC1GAAMAPTMEN1 | |
| SCHEMBL5270827 | 0.89 | KMT2A (0.58) | GAAKDM4EHSD17B10MAPTPOLB | |
| SCHEMBL5268726 | 0.88 | KMT2A (0.57) | RAB9ANPC1GAAPOLBTDP1 | |
| SCHEMBL5267718 | 0.87 | RAB9A (0.52) | RAB9ANPC1GAAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |