Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269177 | 0.91 | RAB9A (0.56) | POLBALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL5268461 | 0.90 | RAB9A (0.54) | POLBALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL5271844 | 0.90 | ALDH1A1 (0.52) | ALDH1A1SGMS1GAAMAPTSMN1; SMN2 | |
| SCHEMBL5272812 | 0.89 | RAB9A (0.56) | POLBALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL5265198 | 0.89 | RAB9A (0.55) | POLBALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL5266973 | 0.88 | RAB9A (0.54) | POLBALDH1A1RAB9ANPC1SGMS1 | |
| SCHEMBL5267412 | 0.88 | RAB9A (0.54) | ALDH1A1RAB9ANPC1SGMS1MEN1 | |
| SCHEMBL5267731 | 0.88 | RAB9A (0.54) | POLBALDH1A1RAB9ANPC1SGMS1 | |
| SCHEMBL5268726 | 0.86 | KMT2A (0.57) | POLBALDH1A1RAB9ANPC1CYP1A2 | |
| SCHEMBL5269255 | 0.86 | RAB9A (0.51) | POLBALDH1A1RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |