SCHEMBL5268548

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5271856	0.92	CHRNA7 (0.41)	KDM1ACHRNA7GABRA1MGLLMALT1
	SCHEMBL5272633	0.88	CHRNA7 (0.43)	KDM1ACHRNA7GABRA1MGLLMALT1
	SCHEMBL4926813	0.88	VNN1 (0.39)	CHRNA7MGLL
	SCHEMBL5270121	0.86	CHRNA7 (0.43)	KDM1ACHRNA7GABRA1MALT1HPGD
	SCHEMBL5266989	0.86	KDM1A (0.51)	KDM1ACHRNA7
	SCHEMBL5270662	0.83	CHRNA7 (0.41)	KDM1ACHRNA7GABRA1MGLLMALT1
	SCHEMBL4936031	0.81	MGLL (0.38)	KDM1ACHRNA7MGLLHTR1A
	SCHEMBL4932048	0.80	MGLL (0.38)	CHRNA7MGLLHTR1A
	SCHEMBL4931012	0.80	CHRNA7 (0.39)	CHRNA7MGLL
	SCHEMBL4924280	0.79	MGLL (0.38)	KDM1ACHRNA7MGLLHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.