Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.49 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13910990 | 0.89 | BACE1 (0.65) | BACE1HSD17B10ALDH1A1ALOX15KMT2A | |
| SCHEMBL17463877 | 0.89 | BACE1 (0.73) | BACE1HSD17B10ALDH1A1ALOX15KMT2A | |
| SCHEMBL16615862 | 0.86 | ALDH1A1 (0.62) | BACE1HSD17B10ALDH1A1ALOX15KMT2A | |
| SCHEMBL2942454 | 0.81 | ALDH1A1 (0.56) | BACE1HSD17B10ALDH1A1ALOX15KMT2A | |
| SCHEMBL17463848 | 0.79 | ALDH1A1 (0.59) | BACE1HSD17B10ALDH1A1ALOX15KMT2A | |
| SCHEMBL30594664 | 0.76 | ALDH1A1 (0.62) | BACE1HSD17B10ALDH1A1ALOX15KMT2A | |
| SCHEMBL7649793 | 0.76 | ALDH1A1 (0.62) | BACE1HSD17B10ALDH1A1ALOX15KMT2A | |
| SCHEMBL6572246 | 0.75 | BACE1 (0.58) | BACE1HSD17B10ALDH1A1ALOX15KMT2A | |
| SCHEMBL6576018 | 0.75 | BACE1 (0.58) | BACE1HSD17B10ALDH1A1ALOX15KMT2A | |
| SCHEMBL6573430 | 0.75 | BACE1 (0.58) | BACE1HSD17B10ALDH1A1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846361-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | claimed |
| WO-2006086374-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-17 | — | — | WO | claimed |
| CN-1997637-A | Novel o-aminophenol derivatives and colorants containing said compounds | WELLA AG (DE) | 2007-07-11 | — | — | CN | disclosed |
| WO-2007020565-A1 | OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2007-02-22 | — | — | WO | disclosed |