Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21999626 | 0.83 | ALDH1A1 (0.48) | BACE1ALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL16429305 | 0.83 | BACE1 (0.68) | BACE1ALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL17463877 | 0.81 | BACE1 (0.73) | BACE1ALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL13910990 | 0.81 | BACE1 (0.65) | BACE1ALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL990770 | 0.79 | ALDH1A1 (0.48) | BACE1ALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL6572246 | 0.76 | BACE1 (0.58) | BACE1ALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL6576018 | 0.76 | BACE1 (0.58) | BACE1ALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL6637403 | 0.76 | TAAR1 (0.47) | BACE1ALDH1A1MEN1LMNAMAPT | |
| SCHEMBL31026737 | 0.76 | ACHE (0.43) | BACE1ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL5268752 | 0.75 | BACE1 (0.56) | BACE1ALDH1A1HSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |