Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270590 | 0.86 | ALDH1A1 (0.53) | HPGDKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL5265874 | 0.86 | SLC16A3 (0.48) | KMT2AMEN1HTTKDM4EALDH1A1 | |
| SCHEMBL5269241 | 0.84 | POLB (0.53) | HPGDKMT2AMEN1HTTKDM4E | |
| SCHEMBL5269276 | 0.83 | ALDH1A1 (0.53) | HPGDKMT2AMEN1HTTKDM4E | |
| SCHEMBL5272599 | 0.81 | TSHR (0.51) | HPGDKMT2AMEN1HTTKDM4E | |
| SCHEMBL5268265 | 0.81 | TDP1 (0.47) | HPGDALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5269115 | 0.80 | HPGD (0.48) | HPGDKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL5266859 | 0.80 | POLB (0.52) | HPGDKMT2AMEN1HTTKDM4E | |
| SCHEMBL5268351 | 0.80 | ALDH1A1 (0.53) | HPGDKMT2AMEN1HTTKDM4E | |
| SCHEMBL5269985 | 0.80 | MAPT (0.49) | HPGDKMT2AMEN1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |