Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 3/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268725 | 0.91 | RAB9A (0.51) | SLC16A3KCNA5TSHRCCKBRMCL1 | |
| SCHEMBL5270341 | 0.87 | MEN1 (0.54) | SLC16A3KCNA5MEN1KMT2AALDH1A1 | |
| SCHEMBL5268835 | 0.86 | HPGD (0.52) | TSHRKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5273547 | 0.85 | TSHR (0.49) | SLC16A3KCNA5TSHRPGRMEN1 | |
| SCHEMBL5269930 | 0.84 | KCNA5 (0.47) | SLC16A3KCNA5TSHRPGRMEN1 | |
| SCHEMBL5268485 | 0.84 | KCNA5 (0.51) | KCNA5KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5270919 | 0.83 | KCNA5 (0.51) | SLC16A3KCNA5TSHRMCL1PGR | |
| SCHEMBL5268920 | 0.82 | KCNA5 (0.47) | SLC16A3KCNA5MCL1MEN1KMT2A | |
| SCHEMBL5266632 | 0.82 | CASP1 (0.42) | KDM4EGSK3BKMT2AALDH1A1 | |
| SCHEMBL5268993 | 0.81 | ALDH1A1 (0.54) | TSHRKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |