Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293703 | 1.00 | MAPT (0.50) | MAPTADRB1ADRB3LMNAMEN1 | |
| SCHEMBL3287682 | 0.88 | ADRB1 (0.50) | MAPTADRB1ADRB3LMNAMEN1 | |
| SCHEMBL5263928 | 0.87 | ATF4 (0.43) | MAPTADRB1ADRB3LMNAMEN1 | |
| SCHEMBL3295260 | 0.87 | ATF4 (0.43) | MAPTADRB1ADRB3LMNAMEN1 | |
| SCHEMBL5264242 | 0.85 | MAPT (0.42) | MAPTADRB1ADRB3LMNAMEN1 | |
| SCHEMBL3288048 | 0.85 | MAPT (0.42) | MAPTADRB1ADRB3LMNAMEN1 | |
| SCHEMBL5202580 | 0.84 | ADRB3 (0.55) | MAPTADRB1ADRB3LMNAMEN1 | |
| SCHEMBL5261882 | 0.83 | ADRB3 (0.49) | MAPTADRB1ADRB3ADRB2 | |
| SCHEMBL12380677 | 0.83 | ADRB3 (0.49) | MAPTADRB1ADRB3ADRB2 | |
| SCHEMBL2294588 | 0.83 | ADRB3 (0.49) | MAPTADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341753-B1 | CYCLOHEXYL(ALKYL)-PROPANOLAMINES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-26 | — | — | EP | claimed |