Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.59 |
| ▸ | NOS1 | P29475 | 1/20 | 0.59 |
| ▸ | NOS2 | P35228 | 1/20 | 0.59 |
| ▸ | PI4KA | P42356 | 1/20 | 0.59 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.59 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.59 |
| ▸ | CHKA | P35790 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Aminopyridine SCHEMBL10589578 | 0.85 | ALDH1A1 (0.59) | NOS3NOS1NOS2PI4KAPI4K2B | |
| 2-Aminopyridine SCHEMBL28747830 | 0.82 | NOS3 (0.80) | NOS3NOS1NOS2PI4KAPI4K2B | |
| 2-Aminopyridine SCHEMBL9487893 | 0.80 | NOS3 (0.52) | NOS3NOS1NOS2PI4KAPI4K2B | |
| 2-Aminopyridine SCHEMBL27970817 | 0.80 | NOS3 (0.84) | NOS3NOS1NOS2PI4KAPI4K2B | |
| SCHEMBL31256490 | 0.79 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL28388870 | 0.79 | CHRM5 (0.61) | CHRM5CHKAMAPTSMN1; SMN2MAOA | |
| 2-Aminopyridine SCHEMBL759357 | 0.78 | NOS3 (0.73) | NOS3NOS1NOS2PI4KAPI4K2B | |
| 2-Chloropyridine SCHEMBL14882379 | 0.78 | TDP1 (0.59) | CHRM5CHKAMAPTSMN1; SMN2MAOA | |
| Pyridine SCHEMBL1830428 | 0.78 | CHRM5 (0.80) | CHRM5CHKAMAPTSMN1; SMN2MAOA | |
| 2-Aminopyridine SCHEMBL6268366 | 0.78 | NOS3 (0.80) | NOS3NOS1NOS2PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366206-B1 | REMOVING HYDROGEN SULPHIDE FROM A GAS MIXTURE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-01-13 | — | — | EP | claimed |
| CN-101125916-A | Biodegradation polymer and its preparing process and application | TIANDA DRUG ZHUHAI CO LTD (CN) | 2008-02-20 | — | — | CN | disclosed |
| EP-1838363-A2 | BIODEGRADABLE COATING COMPOSITIONS COMPRISING BLENDS | SurModics, Inc. (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20060198868-A1 | Biodegradable coating compositions comprising blends | Surmodics Coatings, LLC | 2006-09-07 | — | — | US | disclosed |
| US-7101568-B2 | Methods and compositions for treating solid tumors | GUILFORD PHARMACEUTICALS, INC. (US) | 2006-09-05 | — | — | US | disclosed |
| WO-2006074391-A2 | BIODEGRADABLE COATING COMPOSITIONS COMPRISING BLENDS | SURMODICS, INC. (US) | 2006-07-13 | — | — | WO | disclosed |
| US-20060147491-A1 | Biodegradable coating compositions including multiple layers | Surmodics Coatings, LLC | 2006-07-06 | — | — | US | disclosed |
| US-20060024350-A1 | Biodegradable ocular devices, methods and systems | SURMODICS MD, LLC | 2006-02-02 | — | — | US | disclosed |
| US-20060018948-A1 | Biodegradable implantable medical devices, methods and systems | SURMODICS MD, LLC | 2006-01-26 | — | — | US | disclosed |
| WO-2006002399-A2 | BIODEGRADABLE IMPLANTABLE MEDICAL DEVICES, METHODS AND SYSTEMS | SURMODICS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| US-5912225-A | Biodegradable poly (phosphoester-co-desaminotyrosyl L-tyrosine ester) compounds, compositions, articles and methods for making and using the same | JOHNS HOPKINS UNIV. SCHOOL OF MEDICINE (US) | 1999-06-15 | — | — | US | disclosed |
| WO-1999000446-A9 | SOLUTION POLYMERIZATION OF HIGH MOLECULAR WEIGHT POLY(PHOSPHOESTERS) IN TOLUENE | GUILFORD PHARM INC (US) | 1999-05-06 | — | — | WO | disclosed |
| WO-1998044021-A9 | BIODEGRADABLE TEREPHTHALATE POLYESTER-POLY(PHOSPHATE) POLYMERS, COMPOSITIONS, ARTICLES, AND METHODS FOR MAKING AND USING THE SAME | GUILFORD PHARM INC (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999000446-A1 | SOLUTION POLYMERIZATION OF HIGH MOLECULAR WEIGHT POLY(PHOSPHOESTERS) IN TOLUENE | GUILFORD PHARMACEUTICALS INC. (US) | 1999-01-07 | — | — | WO | disclosed |
| WO-1998058012-A1 | TWO-STAGE SOLUTION POLYMERIZATION OF HIGH MOLECULAR WEIGHT POLY(PHOSPHOESTERS) | GUILFORD PHARMACEUTICALS INC. (US) | 1998-12-23 | — | — | WO | disclosed |
| WO-1998048859-A1 | BIODEGRADABLE COMPOSITIONS COMPRISING POLY(CYCLOALIPHATIC PHOSPHOESTER) COMPOUNDS, ARTICLES, AND METHODS FOR USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 1998-11-05 | — | — | WO | disclosed |
| WO-1998046286-A1 | BIODEGRADABLE COMPOUNDS, COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING THE SAME | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998044021-A1 | BIODEGRADABLE TEREPHTHALATE POLYESTER-POLY(PHOSPHATE) POLYMERS, COMPOSITIONS, ARTICLES, AND METHODS FOR MAKING AND USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 1998-10-08 | — | — | WO | disclosed |
| WO-1998044020-A1 | BIODEGRADABLE POLYMERS CHAIN-EXTENDED BY PHOSPHATES, COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 1998-10-08 | — | — | WO | disclosed |
| US-5235063-A | Acetal derivatives of 3-aryl-2-oxazolidine; antidepressants | DELALANDE S.A. (FR) | 1993-08-10 | — | — | US | disclosed |