Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 8/20 | 0.59 |
| ▸ | NOS2 | P35228 | 8/20 | 0.59 |
| ▸ | NOS1 | P29475 | 5/20 | 0.59 |
| ▸ | PI4KA | P42356 | 1/20 | 0.59 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.59 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626655 | 0.84 | — | — | |
| SCHEMBL35248 | 0.84 | — | — | |
| SCHEMBL28273560 | 0.82 | NOS2 (0.44) | NOS3NOS2NOS1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9013637 | 0.82 | NOS2 (0.44) | NOS3NOS2NOS1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7421394 | 0.82 | NOS2 (0.44) | NOS3NOS2NOS1KMT2AMEN1 | |
| 2-Aminopyridine SCHEMBL28885375 | 0.77 | — | — | |
| 2-Aminopyridine SCHEMBL10484770 | 0.77 | NOS3 (0.89) | NOS3NOS2NOS1PI4KAPI4K2B | |
| 2-Aminopyridine SCHEMBL10484572 | 0.77 | NOS3 (0.89) | NOS3NOS2NOS1PI4KAPI4K2B | |
| 2-Aminopyridine SCHEMBL7007186 | 0.77 | — | — | |
| 2-Aminopyridine SCHEMBL2775240 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838363-A2 | BIODEGRADABLE COATING COMPOSITIONS COMPRISING BLENDS | SurModics, Inc. (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20060198868-A1 | Biodegradable coating compositions comprising blends | Surmodics Coatings, LLC | 2006-09-07 | — | — | US | disclosed |
| WO-2006074391-A2 | BIODEGRADABLE COATING COMPOSITIONS COMPRISING BLENDS | SURMODICS, INC. (US) | 2006-07-13 | — | — | WO | disclosed |
| US-20060147491-A1 | Biodegradable coating compositions including multiple layers | Surmodics Coatings, LLC | 2006-07-06 | — | — | US | disclosed |
| US-20060024350-A1 | Biodegradable ocular devices, methods and systems | SURMODICS MD, LLC | 2006-02-02 | — | — | US | disclosed |
| US-20060018948-A1 | Biodegradable implantable medical devices, methods and systems | SURMODICS MD, LLC | 2006-01-26 | — | — | US | disclosed |
| WO-2006002366-A2 | BIODEGRADABLE OCULAR DEVICES, METHODS AND SYSTEMS | SURMODICS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| WO-2006002399-A2 | BIODEGRADABLE IMPLANTABLE MEDICAL DEVICES, METHODS AND SYSTEMS | SURMODICS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| US-6419709-B1 | SUSTAINED RELEASE; DRUG DELIVERY; USING POLYESTER | GUILFORD PHARMACEUTICALS, INC. | 2002-07-16 | — | — | US | disclosed |
| US-6376644-B1 | POLYESTERS, POLYTHIOESTERS, POLYAMIDES | GUILFORD PHARMACEUTICALS, INC. | 2002-04-23 | — | — | US | disclosed |
| EP-1117441-A2 | BIODEGRADABLE TEREPHTHALATE POLYESTER-POLY(PHOSPHONATE) AND POLYESTER-POLY(PHOSPHITE) COMPOSITIONS, ARTICLES, AND METHODS OF USING THEM | GUILFORD PHARMACEUTICALS INC. (US) | 2001-07-25 | — | — | EP | disclosed |
| US-6166173-A | Biodegradable polymers chain-extended by phosphates, compositions, articles and methods for making and using the same | GUILFORD PHARMACEUTICALS INC. (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000019976-A9 | BIODEGRADABLE TEREPHTHALATE POLYESTER-POLY(PHOSPHONATE) AND POLYESTER-POLY(PHOSPHITE) COMPOSITIONS, ARTICLES, AND METHODS OF USING THEM | GUILFORD PHARM INC (US) | 2000-10-26 | — | — | WO | disclosed |
| WO-2000019976-A2 | BIODEGRADABLE TEREPHTHALATE POLYESTER-POLY(PHOSPHONATE) AND POLYESTER-POLY(PHOSPHITE) COMPOSITIONS, ARTICLES, AND METHODS OF USING THEM | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-13 | — | — | WO | disclosed |
| EP-0971969-A1 | BIODEGRADABLE POLYMERS CHAIN-EXTENDED BY PHOSPHATES, COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998044020-A1 | BIODEGRADABLE POLYMERS CHAIN-EXTENDED BY PHOSPHATES, COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING THE SAME | GUILFORD PHARMACEUTICALS INC. (US) | 1998-10-08 | — | — | WO | disclosed |