Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | TNKS | O95271 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | PARP1 | P09874 | 3/20 | 0.52 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.52 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | QPCT | Q16769 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312103 | 0.86 | CYP19A1 (0.48) | HPGDSMN1; SMN2CYP3A4TNKSALDH1A1 | |
| SCHEMBL311730 | 0.85 | CYP3A4 (0.71) | HPGDSMN1; SMN2CYP3A4TNKSALDH1A1 | |
| SCHEMBL314217 | 0.85 | MAPT (0.71) | HPGDSMN1; SMN2CYP3A4TNKSALDH1A1 | |
| SCHEMBL311199 | 0.79 | TNKS (0.67) | HPGDSMN1; SMN2CYP3A4TNKSALDH1A1 | |
| SCHEMBL311865 | 0.75 | TERT (0.68) | HPGDSMN1; SMN2CYP3A4TNKSALDH1A1 | |
| SCHEMBL311760 | 0.73 | AR (0.68) | HPGDSMN1; SMN2CYP3A4ALDH1A1MAPT | |
| SCHEMBL31238421 | 0.73 | MAPT (0.71) | HPGDSMN1; SMN2CYP3A4TNKSALDH1A1 | |
| SCHEMBL31167385 | 0.71 | CYP3A4 (1.00) | HPGDSMN1; SMN2CYP3A4TNKSALDH1A1 | |
| SCHEMBL157723 | 0.71 | CYP3A4 (1.00) | HPGDSMN1; SMN2CYP3A4TNKSALDH1A1 | |
| SCHEMBL311405 | 0.71 | MAPT (1.00) | HPGDSMN1; SMN2CYP3A4TNKSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838296-A2 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. (CA) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006045096-A2 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. (CA) | 2006-04-27 | — | — | WO | disclosed |