Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | CASP3 | P42574 | 1/20 | 1.00 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 1.00 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 1.00 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 1.00 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.82 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.82 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.82 |
| ▸ | LCK | P06239 | 2/20 | 0.82 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31741263 | 1.00 | MAPT (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL29374176 | 0.91 | LCK (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL10305788 | 0.91 | CSNK2A2 (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL31238426 | 0.91 | MAPT (0.94) | MAPTNPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL3644507 | 0.91 | LCK (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP3A4 | |
| 6-Hydroxyflavone SCHEMBL29628861 | 0.90 | MAPT (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP3A4 | |
| 6-Hydroxyflavone SCHEMBL676594 | 0.90 | MAPT (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL31238388 | 0.88 | MAPT (0.78) | MAPTNPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL311326 | 0.88 | MAPT (0.78) | MAPTNPC1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL10144252 | 0.87 | APP (1.00) | MAPTNPC1RAB9ASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604294-A | ERbeta estrogenic compounds and methods of use | 益特瑞恩公司 | 2025-03-11 | — | — | CN | claimed |
| EP-3808348-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | Biogen MA Inc. (US) | 2021-04-21 | — | — | EP | claimed |
| US-20130183289-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | BIOGEN IDEC MA INC (US) | 2013-07-18 | — | — | US | claimed |
| EP-2200611-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | Biogen Idec MA, Inc. (US) | 2010-06-30 | — | — | EP | claimed |
| WO-2009038684-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) | BIOGEN IDEC MA INC. (US) | 2009-03-26 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| WO-2003026705-A1 | METHODS FOR STERILIZING BIOLOGICAL MATERIALS USING FLAVONOID/FLAVONOL STABILIZERS | CLEARANT, INC. (US) | 2003-04-03 | — | — | WO | claimed |
| US-20030059338-A1 | Methods for sterilizing biological materials using flavonoid/flavonol stabilizers | CLEARANT, INC. | 2003-03-27 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-20260114475-A1 | ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME | MARS, INCORPORATED (US) | 2026-04-30 | — | — | US | disclosed |
| US-20250263774-A1 | DISCOVERING NEW XENOBIOTIC SUBSTRATES OF AN UDP-GLYCOSYLTRANSFERASE WITH A HIGH-THROUGHPUT METHOD | UNIV NORTH TEXAS (US) | 2025-08-21 | — | — | US | disclosed |
| EP-4593631-A1 | ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME | Mars, Incorporated (US) | 2025-08-06 | — | — | EP | disclosed |
| US-20250195452-A1 | ER-BETA ESTROGENIC COMPOUNDS AND METHODS OF USE | IATERION, INC. | 2025-06-19 | — | — | US | disclosed |
| US-20030059338-A1 | Methods for sterilizing biological materials using flavonoid/flavonol stabilizers | CLEARANT, INC. | 2003-03-27 | — | — | US | disclosed |
| US-20030012687-A1 | Methods of sterilizing biological materials | CLEARANT, INC. | 2003-01-16 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| US-6258856-B1 | ADMINISTERING ESTROGEN FOR CATARACT PREVENTION | THE UNIVERSITY OF SYDNEY (AU) | 2001-07-10 | — | — | US | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250195452-A1 | ER-BETA ESTROGENIC COMPOUNDS AND METHODS OF USE | ESR2, ESR1, ESRRB | MAPT 1471/4885NPC1 1013/4885RAB9A 3011/4885 |
| US-20260114475-A1 | ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME | PIGS, TAS2R13, CEL | MAPT 2113/4885NPC1 740/4885RAB9A 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.