SCHEMBL5269062

SCHEMBL5269062

CCCCCCCCCCCCCCCCCCC(CCCN)[Si](C)(C)Cl

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
EPHX1 P07099 1/20 0.46
SPHK1 Q9NYA1 1/20 0.39
OPRM1 P35372 1/20 0.37
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
FDPS P14324 3/20 0.35
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3749524 0.89 LMNA (0.41) DNM1ALDH1A1TSHRSPHK1OPRM1
SCHEMBL5870100 0.73 DNM1 (0.60) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL14840252 0.73 DNM1 (0.60) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL13631066 0.73 DNM1 (0.60) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL5076671 0.73 DNM1 (0.60) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL24641257 0.73 DNM1 (0.60) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL3725398 0.73 LMNA (0.42) DNM1ALDH1A1TSHRSPHK1OPRM1
SCHEMBL14840101 0.73 DNM1 (0.60) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL21862180 0.73 DNM1 (0.60) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL14840172 0.73 DNM1 (0.60) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853967-A2 LOW SURFACE ENERGY POLYMERIC MATERIAL FOR USE IN LIQUID CRYSTAL DISPLAYS The University of North Carolina at Chapel Hill (US) 2007-11-14 EP disclosed
WO-2006084202-A2 LOW SURFACE ENERGY POLYMERIC MATERIAL FOR USE IN LIQUID CRYSTAL DISPLAYS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2006-08-10 WO disclosed