Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492812 | 0.87 | TP53 (0.44) | LMNAPOLBTP53 | |
| SCHEMBL2766694 | 0.84 | F10 (0.47) | LMNAPOLBTP53 | |
| SCHEMBL5264935 | 0.84 | F10 (0.40) | LMNAPOLBTP53MAPT | |
| SCHEMBL2767400 | 0.81 | LMNA (0.46) | LMNAPOLBTP53MAPT | |
| SCHEMBL5263251 | 0.79 | F10 (0.38) | LMNAPOLBTP53MAPT | |
| SCHEMBL4504155 | 0.78 | LMNA (0.44) | LMNAPOLBTP53MAPT | |
| SCHEMBL13632177 | 0.77 | TP53 (0.46) | LMNAPOLBTP53 | |
| SCHEMBL5264920 | 0.74 | F10 (0.44) | LMNAPOLBTP53 | |
| SCHEMBL5266535 | 0.73 | LMNA (0.41) | LMNAPOLBTP53MAPT | |
| SCHEMBL5266476 | 0.72 | F10 (0.46) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836198-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069946-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-07-06 | — | — | WO | disclosed |