SCHEMBL526987

SCHEMBL526987

O=C[C@H](OP(=O)(O)O)[C@H](OP(=O)(O)O)[C@H](O)CO

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.40
AKR1B1 P15121 1/20 0.33
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9737042 1.00 MPI (0.40) MPIAKR1B1PTPN1
SCHEMBL9738005 1.00 MPI (0.40) MPIAKR1B1PTPN1
SCHEMBL9737690 1.00 MPI (0.40) MPIAKR1B1PTPN1
SCHEMBL9736332 1.00 MPI (0.40) MPIAKR1B1PTPN1
SCHEMBL9737340 1.00 MPI (0.40) MPIAKR1B1PTPN1
SCHEMBL9737878 0.96 MPI (0.38) MPIAKR1B1PTPN1
SCHEMBL3080845 0.96 MPI (0.38) MPIAKR1B1PTPN1
SCHEMBL3069342 0.96 MPI (0.38) MPIAKR1B1PTPN1
SCHEMBL18486483 0.96 MPI (0.38) MPIAKR1B1PTPN1
SCHEMBL3069000 0.96 MPI (0.38) MPIAKR1B1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0506772-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A PHOSPHOSUGAR PERSTORP AB (SE) 1992-10-07 EP claimed
WO-1991009604-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A PHOSPHOSUGAR PERSTORP AB (SE) 1991-07-11 WO claimed
US-20250347698-A1 Multi-Omics Biomarker Detection System and Methods for Disease Diagnostics COMPLETE OMICS INC (US) 2025-11-13 US disclosed
US-12370209-B2 Methods for the use of 5′-adenosine diphosphate ribose (ADPR) INVIRSA, INC. (US) 2025-07-29 US disclosed
EP-4463232-A1 SOLID STATE FORMS OF RUCAPARIB TOSYLATE Assia Chemical Industries Ltd. (IL) 2024-11-20 EP disclosed
US-12083114-B2 Inhibitors of SARM1 in combination with neuro-protective agents DISARM THERAPEUTICS, INC. (US) 2024-09-10 US disclosed
US-20240230622-A9 Methods and Systems for Determining Autism Spectrum Disorder Risk LABORATORY CORPORATION OF AMERICA HOLDINGS (US) 2024-07-11 US disclosed
US-20240180892-A1 THERAPY FOR METASTATIC UROTHELIAL CANCER WITH THE ANTIBODY-DRUG CONJUGATE, SACITUZUMAB GOVITECAN (IMMU-132) IMMUNOMEDICS, INC. 2024-06-06 US disclosed
US-20240133865-A1 Methods and Systems for Determining Autism Spectrum Disorder Risk LABORATORY CORPORATION OF AMERICA HOLDINGS (US) 2024-04-25 US disclosed
US-20240091249-A1 METHODS FOR THE USE OF 5'-ADENOSINE DIPHOSPHATE RIBOSE (ADPR) INVIRSA, INC. (US) 2024-03-21 US disclosed
US-11857561-B2 Methods for the use of 5′-adenosine diphosphate ribose (ADPR) INVIRSA, INC. (US) 2024-01-02 US disclosed
US-20070078100-A1 Methods of detecting poly(adp-ribose) polymerase and other nad+ utilizing enzymes THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) 2007-04-05 US disclosed
WO-2005038043-A2 METHODS OF DETECTING POLY (ADP-RIBOSE) POLYMERASE AND OTHER NAD+UTILIZING ENZYMES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2005-04-28 WO disclosed
EP-1458688-A1 QUINAZOLINONE DERIVATIVE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-09-22 EP disclosed
US-6506572-B2 Inhibitor of niacinamide phosphoribosyl transferase (NAPRT) KLINGE PHARMA GMBH (DE) 2003-01-14 US disclosed
US-20020160968-A1 Inhibitors of cellular niacinamide mononucleotide formation and their use in cancer therapy KLINGE PHARMA GMBH 2002-10-31 US disclosed
CN-1345733-A Novel polypeptide-protein 11.55 containing polyadenylic diphosphoribose and polynucleotide for encoding said polypeptide SHANGHAI BIOWINDOW GENE DEV (CN) 2002-04-24 CN disclosed
EP-1031564-A1 Inhibitors of cellular nicotinamide mononucleotide formation and their use in cancer therapy Klinge Pharma GmbH (DE) 2000-08-30 EP disclosed
EP-0506772-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A PHOSPHOSUGAR PERSTORP AB (SE) 1992-10-07 EP disclosed
WO-1991009604-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A PHOSPHOSUGAR PERSTORP AB (SE) 1991-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12370209-B2 Methods for the use of 5′-adenosine diphosphate ribose (ADPR) ADAR, CD38, PARP1 MPI 1767/4885AKR1B1 174/4885PTPN1 4619/4885
US-12083114-B2 Inhibitors of SARM1 in combination with neuro-protective agents SARM1, SMN1; SMN2, SARNP MPI 3498/4885AKR1B1 4448/4885PTPN1 4373/4885
US-11857561-B2 Methods for the use of 5′-adenosine diphosphate ribose (ADPR) ADAR, CD38, PARP1 MPI 1767/4885AKR1B1 174/4885PTPN1 4619/4885
US-20070078100-A1 Methods of detecting poly(adp-ribose) polymerase and other nad+ utilizing enzymes PARP1, PARP11, PARP3 MPI 361/4885AKR1B1 612/4885PTPN1 4435/4885
US-20020160968-A1 Inhibitors of cellular niacinamide mononucleotide formation and their use in cancer therapy NAMPT, NAPRT, NNT MPI 363/4885AKR1B1 599/4885PTPN1 3519/4885
US-20240091249-A1 METHODS FOR THE USE OF 5'-ADENOSINE DIPHOSPHATE RIBOSE (ADPR) ADAR, CD38, PARP1 MPI 1762/4885AKR1B1 167/4885PTPN1 4648/4885
US-20240180892-A1 THERAPY FOR METASTATIC UROTHELIAL CANCER WITH THE ANTIBODY-DRUG CONJUGATE, SACITUZUMAB GOVITECAN (IMMU-132) PARP2, CD22, DOCK2 MPI 1318/4885AKR1B1 3956/4885PTPN1 3238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.