DOCK2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL13977765	1.00	1/20
SCHEMBL29627161	1.00	1/20
SCHEMBL13977382	0.69	1/20
SCHEMBL13977767	0.60	1/20
SCHEMBL14712961	0.60	1/20
SCHEMBL14712901	0.57	1/20
SCHEMBL10026592	0.53	1/20
SCHEMBL3763333	0.47	1/20
SCHEMBL3763335	0.47	1/20
SCHEMBL7311865	0.47	1/20
SCHEMBL7311870	0.47	1/20
SCHEMBL5199097	0.45	1/20
SCHEMBL10808424	0.44	1/20
SCHEMBL10808428	0.44	1/20
SCHEMBL11461138	0.44	1/20
SCHEMBL13977390	0.43	1/20
SCHEMBL97837	0.43	1/20
SCHEMBL629076	0.43	1/20
SCHEMBL10137939	0.42	1/20
SCHEMBL11319367	0.42	1/20

Clinical trials — most relevant to DOCK2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)	PHASE4	RECRUITING
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment	PHASE2/PHASE3	RECRUITING
Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency	PHASE2	ACTIVE_NOT_RECRUITING
Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100	PHASE1/PHASE2	COMPLETED
Interleukin-2 Treatment for Wiskott-Aldrich Syndrome	PHASE1	COMPLETED
Family Myopia Study	nan	COMPLETED
Markers and Mechanisms of Macrovascular Disease in IDDM	nan	COMPLETED
Identification of Genetic Basis of Atrioventricular Conduction Defects: From Congenital Forms to Degenerative Forms	nan	UNKNOWN
PCD New Gene Discovery	nan	COMPLETED
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science	nan	RECRUITING
Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis.	nan	COMPLETED
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia	nan	COMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events	nan	COMPLETED
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study	nan	UNKNOWN
The Clinical Study of Sex Chromosome Variants	nan	COMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma	nan	RECRUITING
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
Multidimensional Dynamic Early Warning System for Neonatal Necrotizing Enterocolitis: A Multicenter Clinical Study	nan	NOT_YET_RECRUITING
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia	nan	UNKNOWN
Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer	nan	UNKNOWN
Genetic Analysis of Familial Melanoma	nan	COMPLETED
Biochemical and Phenotypical Aspects of Smith-Lemli-Opitz Syndrome and Related Disorders of Cholesterol Metabolism	nan	RECRUITING
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Chromosome 9 P Minus Syndrome	nan	RECRUITING
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies	nan	RECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients	nan	RECRUITING
Identification of Genomic Loci Determining Susceptibility to the Development of High Myopia	nan	COMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a DOCK2 binder may also engage these)

Protein	Name	Similarity
Q8C3J5	—	1.000	Q8C3J5 →
DOCK5	Dedicator of cytokinesis protein 5	1.000	landscape →
B2RY04	—	1.000	B2RY04 →
Q8BUR4	—	0.999	Q8BUR4 →
Q14185	—	0.998	Q14185 →
A8WTE8	—	0.991	A8WTE8 →
Q19555	—	0.991	Q19555 →
Q9VRX1	—	0.990	Q9VRX1 →
Q811G0	—	0.990	Q811G0 →
Q9TXI7	—	0.989	Q9TXI7 →
Q19317	—	0.989	Q19317 →
O01763	—	0.989	O01763 →
O74925	—	0.989	O74925 →
Q24314	—	0.989	Q24314 →
Q3SYG4	—	0.989	Q3SYG4 →
Q54F23	—	0.989	Q54F23 →
Q8LPK4	—	0.988	Q8LPK4 →
Q9W3E1	—	0.988	Q9W3E1 →
Q5XG71	—	0.988	Q5XG71 →
Q9VX91	—	0.988	Q9VX91 →
Q61586	—	0.988	Q61586 →
Q9STV0	—	0.988	Q9STV0 →
Q8WUM0	—	0.988	Q8WUM0 →
Q8BX57	—	0.988	Q8BX57 →
Q19954	—	0.988	Q19954 →
Q09743	—	0.988	Q09743 →
Q5PQS3	—	0.988	Q5PQS3 →
F4IP13	—	0.988	F4IP13 →
Q8STE5	—	0.987	Q8STE5 →
Q9VYG1	—	0.987	Q9VYG1 →