Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 6/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269184 | 0.88 | ALDH1A1 (0.55) | MAP2ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL4914710 | 0.71 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL42364 | 0.69 | MAP2 (1.00) | MAP2GPR35ALDH1A1KDM4EHPGD | |
| SCHEMBL5270273 | 0.68 | MAP2 (0.55) | MAP2GPR35ALDH1A1KDM4EHPGD | |
| SCHEMBL5268565 | 0.67 | MAP2 (0.41) | MAP2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL16195543 | 0.66 | SMN1; SMN2 (0.67) | ALDH1A1HPGDGAA | |
| SCHEMBL5269231 | 0.65 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL5335425 | 0.65 | ACACB (0.39) | MAP2MEN1KMT2AHTT | |
| SCHEMBL20570856 | 0.64 | MAP2 (0.73) | MAP2GPR35ALDH1A1KDM4EHPGD | |
| SCHEMBL22817013 | 0.63 | HAO1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |