Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573999 | 0.80 | HRH3 (0.35) | LMNAMAPTNPY1RNPY2RNPY4R | |
| SCHEMBL11937222 | 0.71 | NPY1R (0.62) | LMNAMAPTNPY1RNPY2RNPY4R | |
| SCHEMBL4228938 | 0.71 | PTGES (0.57) | LMNAMAPTNPY1RNPY2RNPY4R | |
| SCHEMBL5269231 | 0.70 | ALDH1A1 (0.52) | LMNAMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL270820 | 0.69 | NPY1R (0.60) | LMNAMAPTNPY1RNPY2RNPY4R | |
| SCHEMBL18210657 | 0.69 | NPY1R (0.60) | LMNAMAPTNPY1RNPY2RNPY4R | |
| SCHEMBL13403331 | 0.69 | NPY1R (0.51) | LMNAMAPTNPY1RNPY2RNPY4R | |
| SCHEMBL4022950 | 0.69 | ALDH1A1 (0.51) | MAP2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL5299189 | 0.69 | PTGES (0.52) | MAP2MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL5281847 | 0.68 | KDM4E (0.48) | MAP2MAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838669-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006077365-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |