Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 10/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.56 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943023 | 0.92 | SLC6A9 (0.72) | SLC6A9SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL8722264 | 0.90 | SLC6A9 (0.61) | SLC6A9SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL8204423 | 0.89 | SLC6A9 (0.60) | SLC6A9SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL13780465 | 0.89 | SLC6A9 (0.77) | SLC6A9SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL7939788 | 0.88 | SLC6A9 (0.69) | SLC6A9SLC6A4HRH3SLC6A2SLC6A3 | |
| Toluene SCHEMBL8723129 | 0.88 | SLC6A9 (0.56) | SLC6A9SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL5268496 | 0.86 | SLC6A9 (0.63) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL8722262 | 0.86 | SLC6A9 (0.67) | SLC6A9SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4300396 | 0.85 | SLC6A9 (0.72) | SLC6A9SLC6A4HRH3SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL7317614 | 0.84 | SLC6A4 (0.88) | SLC6A9SLC6A4HRH3SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270483-A1 | PROCESS FOR THE PREPARATION OF ARYLOXYPROPYLAMINES | DIPHARMA FRANCIS S.R.L. (IT) | 2007-11-22 | — | — | US | claimed |
| EP-1857435-A2 | A process for the preparation of aryloxypropylamines | Dipharma Francis S.r.l. (IT) | 2007-11-21 | — | — | EP | claimed |
| WO-2010010412-A2 | METHOD FOR THE PREPARATION OF N-METHYL-ARYLOXY-PROPANAMINE DERIVATIVES | LUKÁCS, Gyula (HU) | 2010-01-28 | — | — | WO | disclosed |
| US-20070270483-A1 | PROCESS FOR THE PREPARATION OF ARYLOXYPROPYLAMINES | DIPHARMA FRANCIS S.R.L. (IT) | 2007-11-22 | — | — | US | disclosed |
| EP-1857435-A2 | A process for the preparation of aryloxypropylamines | Dipharma Francis S.r.l. (IT) | 2007-11-21 | — | — | EP | disclosed |
| EP-0617006-B1 | N-Substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and procedure for their preparation | PLIVA PHARM & CHEM WORKS (HR) | 1998-05-06 | — | — | EP | disclosed |
| US-5618968-A | N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation | PLIVA FARMACEUTSKA KEMIJSKA, PREHRAMBENA I KOZMETICKA INDUSTRIJA, DIONICKO DRUSTVO (HR) | 1997-04-08 | — | — | US | disclosed |
| EP-0617006-A1 | N-subtituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation | PLIVA d.d. ZAGREB (HR) | 1994-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270483-A1 | PROCESS FOR THE PREPARATION OF ARYLOXYPROPYLAMINES | NAT1, C1S, PAH | SLC6A9 221/4885SLC6A4 310/4885HRH3 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.