Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277132 | 0.87 | KMT2A (0.68) | MAPK1LMNAKMT2AHTTNPSR1 | |
| SCHEMBL278453 | 0.86 | HDAC3 (0.49) | MAPK1LMNAKMT2AHTTPOLB | |
| SCHEMBL276182 | 0.85 | HTT (0.66) | MAPK1LMNAKMT2AHTTNPSR1 | |
| SCHEMBL279935 | 0.81 | KMT2A (0.54) | MAPK1LMNAKMT2AHTTPOLB | |
| SCHEMBL277005 | 0.81 | HTT (0.50) | MAPK1LMNAKMT2AHTTPOLB | |
| SCHEMBL12313814 | 0.78 | ALDH1A1 (0.60) | MAPK1LMNAKMT2AHTTPOLB | |
| SCHEMBL12265884 | 0.78 | YEATS4 (0.60) | MAPK1LMNAKMT2AHTTPOLB | |
| SCHEMBL1587750 | 0.76 | HPGD (0.58) | MAPK1LMNANPSR1PPARGNCOA2 | |
| SCHEMBL70027 | 0.76 | NPSR1 (0.67) | MAPK1LMNAKMT2ANPSR1PPARG | |
| SCHEMBL12265886 | 0.76 | YEATS4 (0.61) | MAPK1LMNAKMT2AHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101076519-A | Amide compound and thrombopoietin receptor activator | NISSAN CHEMICAL IND LTD (JP) | 2007-11-21 | — | — | CN | disclosed |
| EP-1845090-A1 | AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |