Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.38 |
| ▸ | TUBB | P07437 | 3/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780471 | 0.84 | MAPT (0.45) | CYP1A2CYP2C19ALDH1A1HPGDXBP1 | |
| SCHEMBL5272473 | 0.84 | MAPT (0.46) | CYP1A2CYP2C19ALDH1A1HPGDXBP1 | |
| SCHEMBL4776998 | 0.82 | MAPT (0.45) | CYP1A2CYP2C19ALDH1A1HPGDXBP1 | |
| SCHEMBL5269908 | 0.81 | ALDH1A1 (0.44) | CYP1A2CYP2C19ALDH1A1HPGDXBP1 | |
| SCHEMBL5573980 | 0.76 | MAPT (0.40) | CYP1A2CYP2C19ALDH1A1HPGDXBP1 | |
| SCHEMBL5266914 | 0.76 | MAPT (0.41) | CYP1A2CYP2C19ALDH1A1HPGDXBP1 | |
| SCHEMBL4777292 | 0.75 | MAPT (0.43) | CYP1A2CYP2C19ALDH1A1HPGDXBP1 | |
| SCHEMBL4839135 | 0.75 | MAPT (0.39) | CYP1A2CYP2C19ALDH1A1HPGDXBP1 | |
| SCHEMBL5571402 | 0.74 | KDM4E (0.43) | CYP1A2CYP2C19ALDH1A1HPGDXBP1 | |
| SCHEMBL5570201 | 0.74 | MAPT (0.46) | CYP1A2CYP2C19ALDH1A1HPGDXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |