Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | BHMT | Q93088 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096345 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL4657298 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL31363055 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL11618406 | 0.98 | TSHR (0.57) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL30552821 | 0.89 | LMNA (0.52) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL10794932 | 0.89 | LMNA (0.52) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL10604173 | 0.89 | LMNA (0.52) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL11039360 | 0.89 | LMNA (0.52) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL15823201 | 0.87 | TSHR (0.50) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL14809409 | 0.87 | TSHR (0.50) | TSHRLMNANFKB1PMP22GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084423-A1 | MULTILAYER STRUCTURES COMPRISING A BARRIER LAYER AND THEIR USE TO CONVEY FLUIDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011084421-A1 | HOLLOW STRUCTURES AND ASSOCIATED METHODS FOR CONVEYING REFRIGERANT FLUIDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-14 | — | — | WO | disclosed |