SCHEMBL4657298

SCHEMBL4657298

O=C(O)CCCCCC(C(=O)O)C(CCCCCC(=O)O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.60
LMNA P02545 2/20 0.60
NFKB1 P19838 1/20 0.60
PMP22 Q01453 1/20 0.60
GSTK1 Q9Y2Q3 2/20 0.54
FFAR4 Q5NUL3 3/20 0.52
FFAR1 O14842 3/20 0.52
GPR84 Q9NQS5 4/20 0.50
ALDH1A1 P00352 3/20 0.50
BHMT Q93088 1/20 0.50
ENPEP Q07075 1/20 0.48
PPARG P37231 4/20 0.48
PPARD Q03181 4/20 0.48
PPARA Q07869 4/20 0.48
HDAC11 Q96DB2 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
TLR2 O60603 1/20 0.48
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11096345 1.00 TSHR (0.60) TSHRLMNANFKB1PMP22GSTK1
SCHEMBL527023 1.00 TSHR (0.60) TSHRLMNANFKB1PMP22GSTK1
SCHEMBL31363055 1.00 TSHR (0.60) TSHRLMNANFKB1PMP22GSTK1
SCHEMBL11618406 0.98 TSHR (0.57) TSHRLMNANFKB1PMP22GSTK1
SCHEMBL30552821 0.89 LMNA (0.52) TSHRLMNANFKB1PMP22GSTK1
SCHEMBL10794932 0.89 LMNA (0.52) TSHRLMNANFKB1PMP22GSTK1
SCHEMBL10604173 0.89 LMNA (0.52) TSHRLMNANFKB1PMP22GSTK1
SCHEMBL11039360 0.89 LMNA (0.52) TSHRLMNANFKB1PMP22GSTK1
SCHEMBL15823201 0.87 TSHR (0.50) TSHRLMNANFKB1PMP22GSTK1
SCHEMBL14809409 0.87 TSHR (0.50) TSHRLMNANFKB1PMP22GSTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7241915-B2 Process for inhibition of polymerization of (meth)acrylate ester NIPPON SHOKUBAI CO., LTD. (JP) 2007-07-10 US claimed
US-10023522-B2 Hydroxyalkyl acrylate and method for producing same NIPPON SHOKUBAI CO., LTD. (JP) 2018-07-17 US disclosed
EP-2899180-B1 HYDROXYALKYL ACRYLATE AND METHOD FOR PRODUCING SAME NIPPON CATALYTIC CHEM IND (JP) 2018-01-31 EP disclosed
US-20150225330-A1 HYDROXYALKYL ACRYLATE AND METHOD FOR PRODUCING SAME NIPPON SHOKUBAI CO., LTD. (JP) 2015-08-13 US disclosed
EP-2899180-A1 HYDROXYALKYL ACRYLATE AND METHOD FOR PRODUCING SAME Nippon Shokubai Co., Ltd. (JP) 2015-07-29 EP disclosed
CN-104640835-A Hydroxyalkyl acrylate and process for producing the same NIPPON CATALYTIC CHEM IND 2015-05-20 CN disclosed
CN-101679199-B Method for distilling liquid containing easily polymerizable compound NIPPON CATALYTIC CHEM IND 2013-05-29 CN disclosed
EP-1371628-B1 Production process for hydroxyalkyl (meth)acrylate NIPPON CATALYTIC CHEM IND (JP) 2011-12-28 EP disclosed
CN-101679199-A Method for distilling liquid containing easily polymerizable compound NIPPON CATALYTIC CHEM IND 2010-03-24 CN disclosed
CN-100448839-C Process for preparing hydroxyalkyl (meth) acrylates NIPPON CATALYTIC CHEM IND (JP) 2009-01-07 CN disclosed
EP-1371628-A2 Production process for hydroxyalkyl (meth)acrylate Nippon Shokubai Co., Ltd. (JP) 2003-12-17 EP disclosed
EP-1371629-A1 Process for the preparation of hydroxyalkyl(meth)acrylate Nippon Shokubai Co., Ltd. (JP) 2003-12-17 EP disclosed
US-20030229244-A1 Hydroxyalkyl (meth)acrylate and its production process NIPPON SHOKUBAI CO., LTD. 2003-12-11 US disclosed
US-20030229243-A1 Production process for hydroxyalkyl (meth) acrylate NIPPON SHOKUBAI CO., LTD. 2003-12-11 US disclosed
CN-1443748-A Polymerization inhibition of (methyl) acrylic ester NIPPON CATALYTIC CHEM IND (JP) 2003-09-24 CN disclosed
US-20030176725-A1 Process for inhibition of polymerization of (meth) acrylate ester NIPPON SHOKUBAI CO., LTD. 2003-09-18 US disclosed
EP-1344764-A2 Process for the inhibition of polymerization of (meth)acrylate esters Nippon Shokubai Co., Ltd. (JP) 2003-09-17 EP disclosed
US-6465681-B2 Production process for hydroxyalkyl (meth)acrylate NIPPON SHOKUBAI CO., LTD. (JP) 2002-10-15 US disclosed
EP-1219588-A2 Production process for hydroxyalkyl (meth)acrylate Nippon Shokubai Co., Ltd. (JP) 2002-07-03 EP disclosed
US-20020082443-A1 Production process for hydroxyalkyl (meth)acrylate NIPPON SHOKUBAI CO., LTD. (JP) 2002-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150225330-A1 HYDROXYALKYL ACRYLATE AND METHOD FOR PRODUCING SAME HAO2, HACL2, ACR TSHR 4321/4885LMNA 3524/4885NFKB1 1906/4885
US-10023522-B2 Hydroxyalkyl acrylate and method for producing same HAO2, HACL2, ACR TSHR 4321/4885LMNA 3524/4885NFKB1 1906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.