Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15726040 | 0.83 | PTGER1 (0.57) | MEN1KMT2APTGER1MAPTTDP1 | |
| SCHEMBL16369625 | 0.83 | CTSV (0.48) | CTSVCTSLMEN1KMT2AMAPT | |
| SCHEMBL3093865 | 0.82 | CTSV (0.58) | CTSVCTSLTSHRMEN1KMT2A | |
| SCHEMBL6597868 | 0.80 | KMT2A (0.44) | CTSVCTSLMEN1KMT2AMAPT | |
| SCHEMBL12253970 | 0.80 | PTPN1 (0.47) | CTSVCTSLMEN1KMT2APTGER1 | |
| SCHEMBL24983833 | 0.79 | PTGER1 (0.60) | CTSVCTSLPTGER1MAPTTDP1 | |
| SCHEMBL30141251 | 0.79 | PTGER1 (0.60) | CTSVCTSLPTGER1MAPTTDP1 | |
| SCHEMBL1162221 | 0.79 | PTGER1 (0.54) | CTSVCTSLMEN1KMT2APTGER1 | |
| SCHEMBL14605182 | 0.79 | TSHR (0.61) | CTSVCTSLTSHRMEN1KMT2A | |
| SCHEMBL11516740 | 0.78 | MEN1 (0.48) | TSHRMEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217022-B2 | GLP-1 receptor agonist compounds having stabilized regions | ASTRAZENECA PHARMACEUTICALS LP (US) | 2015-12-22 | — | — | US | disclosed |
| US-20130184203-A1 | GLP-1 RECEPTOR AGONIST COMPOUNDS HAVING STABILIZED REGIONS | ASTRAZENECA PHARMACEUTICALS LP (US) | 2013-07-18 | — | — | US | disclosed |
| EP-2598161-A2 | GLP-1 RECEPTOR AGONIST COMPOUNDS HAVING STABILIZED REGIONS | Amylin Pharmaceuticals, LLC (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012015975-A2 | GLP-1 RECEPTOR AGONIST COMPOUNDS HAVING STABILIZED REGIONS | AMYLIN PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184203-A1 | GLP-1 RECEPTOR AGONIST COMPOUNDS HAVING STABILIZED REGIONS | GLP1R, GIPR, GCGR | CTSV 1553/4885CTSL 2699/4885TSHR 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.