Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15871971 | 0.84 | HTR1A (0.53) | MEN1KMT2AMAPTHTR1AADRA1D | |
| SCHEMBL15123629 | 0.83 | MAPT (0.46) | MEN1KMT2AMAPTPTPN1HTR1A | |
| SCHEMBL14228268 | 0.82 | MGMT (0.48) | MEN1KMT2AMAPTPTPN1PIN1 | |
| SCHEMBL7793968 | 0.79 | MEN1 (0.47) | MEN1KMT2AMAPTPTPN1HTR1A | |
| SCHEMBL9007594 | 0.78 | MGMT (0.50) | MEN1KMT2AMAPTPTPN1PIN1 | |
| SCHEMBL527106 | 0.78 | CTSV (0.52) | MEN1KMT2AMAPTPTPN1HTR1A | |
| SCHEMBL8031159 | 0.78 | PIN1 (0.48) | MEN1KMT2AMAPTPTPN1HTR1A | |
| SCHEMBL27388637 | 0.78 | HTR1A (0.55) | MEN1KMT2AHTR1AADRA1DADRA1A | |
| SCHEMBL6058052 | 0.78 | MAPT (0.42) | MEN1KMT2AMAPTPTPN1HTR1A | |
| SCHEMBL7390982 | 0.78 | KMT2A (0.44) | MEN1KMT2ANPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171446-A | Indazole compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1979-10-16 | — | — | US | disclosed |