SCHEMBL527178

SCHEMBL527178

CCCCCCCCCCc1ccc(C(=O)C(F)(F)F)cc1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.67
MLYCD O95822 2/20 0.61
THRA P10827 9/20 0.60
THRB P10828 9/20 0.60
RARB P10826 5/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
ALDH1A1 P00352 1/20 0.59
RARA P10276 1/20 0.59
MAPT P10636 1/20 0.59
MTOR P42345 1/20 0.59
PLA2G1B P04054 1/20 0.55
ATG4B Q9Y4P1 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11134588 1.00 FAAH (0.67) FAAHMLYCDTHRATHRBRARB
SCHEMBL25245358 1.00 FAAH (0.67) FAAHMLYCDTHRATHRBRARB
SCHEMBL26660482 1.00 FAAH (0.67) FAAHMLYCDTHRATHRBRARB
SCHEMBL3266747 1.00 FAAH (0.67) FAAHMLYCDTHRATHRBRARB
SCHEMBL9097134 1.00 FAAH (0.67) FAAHMLYCDTHRATHRBRARB
SCHEMBL26660468 0.98 FAAH (0.64) FAAHMLYCDTHRATHRBRARB
SCHEMBL3266774 0.93 MLYCD (0.58) FAAHMLYCDTHRATHRBRARB
SCHEMBL9751026 0.91 FAAH (0.57) FAAHMLYCDTHRATHRBRARB
SCHEMBL9751024 0.91 FAAH (0.57) FAAHMLYCDTHRATHRBRARB
SCHEMBL16487163 0.89 RARB (0.66) FAAHMLYCDTHRATHRBRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0744429-A2 Stoving lacquer based on an epoxy resin containing an alkylidene polyphenol having an acid-functional group Vianova Resins GmbH (DE) 1996-11-27 EP claimed
US-20160195491-A1 ION SELECTIVE ELECTRODE RAO K JAGAN M (US) 2016-07-07 US disclosed
US-20140174923-A1 ION SELECTIVE ELECTRODE RAO K JAGAN M (US) 2014-06-26 US disclosed
WO-2012015213-A2 METHOD FOR MANUFACTURING AMPEROMETRY-BASED MICRO-ION SELECTIVE ELECTRODE, AMPEROMETRY-BASED MICRO-ION SELECTIVE ELECTRODE MANUFACTURED THEREBY, AND METHOD FOR ELECTROCHEMICALLY DETERMINING ION-CONCENTRATION USING SAME (주)더바이오 (KR) 2012-02-02 WO disclosed
US-6635683-B1 Membrane containing onium salt and aromatic boric diester compounds; rapid measurement in body fluids; high sensitivity and selectivity; long life TOKUYAMA CORPORATION (JP) 2003-10-21 US disclosed
EP-1096251-A1 FILM RESPONSIVE TO BICARBONATE ION TOKUYAMA CORPORATION (JP) 2001-05-02 EP disclosed
US-6177417-B1 HOST MATERIAL FOR ION SENSORS Pyun, Hyung Jung (KR) 2001-01-23 US disclosed
US-5531870-A Potentiometric ion determinations using enhanced selectivity asymmetric ion-selective membranes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-02 US disclosed
US-5415746-A Sampling and passing through membranes and electrolysis E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-05-16 US disclosed
EP-0603742-A2 Potentiometric ion determinations using enhanced selectivity asymmetric ion-selective membrane electrodes E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 1994-06-29 EP disclosed
US-5013421-A Microporous tube impregnated with polymer matrix BIO-CHEM LABORATORY SYSTEMS, INC. 1991-05-07 US disclosed
US-5011588-A Porous membrane support impregnated with plastic RAO K JAGAN M (US) 1991-04-30 US disclosed
EP-0024191-B1 REFERENCE ELEMENTS, ION-SELECTIVE ELECTRODES CONTAINING SAID ELEMENTS AND METHOD OF PREPARING SAID ELEMENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-04-04 EP disclosed
US-4263343-A SILVER, ELECTROLYTE, OXIDER OR SILVER HALIDE EMULSION EASTMAN KODAK COMPANY (US) 1981-04-21 US disclosed
EP-0024191-A2 Reference elements, ion-selective electrodes containing said elements and method of preparing said elements EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-02-25 EP disclosed