Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14884988 | 0.75 | UGT2B17 (0.30) | — | |
| SCHEMBL30694197 | 0.75 | TSHR (0.32) | TSHR | |
| SCHEMBL17441217 | 0.75 | TSHR (0.32) | TSHR | |
| SCHEMBL10257016 | 0.74 | TSHR (0.33) | TSHRCDC25BKDM4EMEN1ALDH1A1 | |
| SCHEMBL29741176 | 0.72 | — | — | |
| SCHEMBL23782836 | 0.71 | ALDH1A1 (0.38) | TSHRKDM4EALDH1A1GAAMAPT | |
| SCHEMBL29740958 | 0.71 | SMN1; SMN2 (0.45) | TSHRKDM4EALDH1A1GAAMAPT | |
| SCHEMBL23782959 | 0.71 | SMN1; SMN2 (0.45) | TSHRKDM4EALDH1A1GAAMAPT | |
| SCHEMBL6441867 | 0.70 | TSHR (0.32) | TSHR | |
| SCHEMBL3955713 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140162980-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140162980-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-12 | — | — | US | disclosed |
| EP-2598487-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | Syngenta Participations AG (CH) | 2013-06-05 | — | — | EP | disclosed |
| CN-103038217-A | Novel microbiocidal dioxime ether derivatives | SYNGENTA PARTICIPATIONS AG | 2013-04-10 | — | — | CN | disclosed |
| WO-2012013754-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012013754-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140162980-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | PRDX4, PRDX6, DDT | TSHR 4391/4885CDC25B 188/4885KDM4E 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.