Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266768 | 0.83 | CLK1 (0.52) | POLBALDH1A1HTTALPLALPI | |
| SCHEMBL5271504 | 0.83 | HPGD (0.53) | POLBALDH1A1HPGDGAAKMT2A | |
| SCHEMBL5269232 | 0.83 | CLK1 (0.49) | POLBALPLALPIALPGCLK1 | |
| SCHEMBL5269902 | 0.82 | CLK1 (0.51) | POLBALDH1A1ALPLALPIALPG | |
| SCHEMBL5269043 | 0.82 | KMT2A (0.41) | POLBALDH1A1HPGDKDM4EGAA | |
| SCHEMBL5271991 | 0.81 | CDK14 (0.55) | POLBALPLALPIALPGCLK1 | |
| SCHEMBL5271516 | 0.80 | SMYD3 (0.55) | POLBHPGDALPLALPIALPG | |
| SCHEMBL18478351 | 0.78 | HPGD (0.69) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL4284373 | 0.77 | CDK14 (0.48) | POLBALDH1A1KDM4EALPLALPI | |
| SCHEMBL4292708 | 0.77 | CDK14 (0.48) | POLBKDM4EALPLALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |