Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30615622 | 0.89 | DAO (0.54) | DAOGSK3BMEN1KMT2APABPC1 | |
| SCHEMBL1699095 | 0.88 | DAO (0.62) | DAOGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4629477 | 0.85 | DAO (0.58) | DAOGSK3BMEN1KMT2AGABRP | |
| SCHEMBL1699133 | 0.84 | DAO (0.58) | DAOGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL530637 | 0.81 | SMN1; SMN2 (0.65) | DAOGSK3BMEN1KMT2APABPC1 | |
| SCHEMBL15427100 | 0.81 | DAO (0.54) | DAOGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11556143 | 0.81 | DAO (0.54) | DAOMEN1KMT2AGABRPGABRD | |
| SCHEMBL11554147 | 0.81 | ALDH1A1 (0.58) | DAOMEN1KMT2AGABRPGABRD | |
| SCHEMBL30615446 | 0.81 | DAO (0.54) | DAOMEN1KMT2AGABRPGABRD | |
| SCHEMBL11435447 | 0.81 | DAO (0.57) | DAOGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012015693-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-02-02 | — | — | WO | disclosed |