Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.31 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26688718 | 0.81 | PARG (0.33) | PARP1PARGALDH1A1MAPTPDE3A | |
| SCHEMBL31605865 | 0.81 | PARG (0.33) | PARP1PARGALDH1A1MAPTPDE3A | |
| SCHEMBL27142990 | 0.76 | MAP2 (0.42) | PGRPARP1ALDH1A1LMNAMAPT | |
| SCHEMBL29937099 | 0.76 | MAP2 (0.42) | PGRPARP1ALDH1A1LMNAMAPT | |
| SCHEMBL25206708 | 0.75 | DAO (0.41) | PGRPARP1ALDH1A1LMNAMAPT | |
| SCHEMBL29936825 | 0.75 | DAO (0.41) | PGRPARP1ALDH1A1LMNAMAPT | |
| SCHEMBL22393852 | 0.73 | PGR (0.37) | PGRPARP1ALDH1A1LMNAMAPT | |
| SCHEMBL30504352 | 0.73 | PGR (0.37) | PGRPARP1ALDH1A1LMNAMAPT | |
| SCHEMBL525865 | 0.71 | PARP1 (0.49) | PARP1PARGALDH1A1LMNAMAPT | |
| SCHEMBL16033113 | 0.70 | PARG (0.56) | PARP1PARGALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014109-A1 | HETEROCYCLIC SULFONAMIDES AS INHIBITORS OF TRANSFER RNA SYNTHETASE FOR USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |