Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 5/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 4/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260759 | 0.73 | ELANE (0.43) | ELANEPARP1TNKSTNKS2DHODH | |
| SCHEMBL6260768 | 0.73 | ELANE (0.43) | ELANEPARP1TNKSTNKS2DHODH | |
| SCHEMBL5273541 | 0.72 | SCN3A (0.53) | ELANEHDAC1DHODHSCN3ASCN9A | |
| SCHEMBL27638674 | 0.71 | PARP1 (0.36) | PARP1TNKSTNKS2DHODHMEN1 | |
| SCHEMBL5273550 | 0.71 | PARP1 (0.36) | PARP1TNKSTNKS2DHODHMEN1 | |
| SCHEMBL4757958 | 0.68 | ELANE (0.43) | ELANEHTR2CMEN1KMT2ACYP1A2 | |
| SCHEMBL3274805 | 0.68 | ELANE (0.43) | ELANEHTR2CMEN1KMT2ACYP1A2 | |
| SCHEMBL27566521 | 0.67 | GAA (0.43) | ELANERIPK1MEN1KMT2AMAPT | |
| SCHEMBL27566520 | 0.67 | GAA (0.43) | ELANERIPK1MEN1KMT2AMAPT | |
| SCHEMBL29834190 | 0.67 | ESR1 (0.56) | PARP1TNKSTNKS2ACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587793-B1 | ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA | BIOMERIEUX SA (FR) | 2007-11-28 | — | — | EP | disclosed |
| CN-100343234-C | Enzyme substrates, culture media containing same and use thereof in order to detect aminopeptidase activity and/or differentiate gram-positive bacteria from gram-negative bacteria | BIOMERIEUX SA (FR) | 2007-10-17 | — | — | CN | disclosed |
| US-7223865-B2 | Chromogenic compounds, and use thereof as enzyme substrates | BIOMERIEUX (FR) | 2007-05-29 | — | — | US | disclosed |
| CN-1745066-A | Enzyme substrates, culture media containing same and use thereof in order to detect aminopeptidase activity and/or differentiate gram-positive bacteria from gram-negative bacteria | BIOMERIEUX SA (FR) | 2006-03-08 | — | — | CN | disclosed |
| US-20060035306-A1 | Enzyme substrates, culture media containing same and use thereof in order to detect aminopeptidase activity and/or differentiate gram-positive bacteria from gram-negative bacteria | BIOMERIEUX (FR) | 2006-02-16 | — | — | US | disclosed |
| EP-1587793-A1 | ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA | BIOMERIEUX (FR) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004069804-A1 | ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA | BIOMERIEUX (FR) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035306-A1 | Enzyme substrates, culture media containing same and use thereof in order to detect aminopeptidase activity and/or differentiate gram-positive bacteria from gram-negative bacteria | ANPEP, RNPEP, DNPEP | ELANE 267/4885PARP1 3796/4885TNKS 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.