Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274805 | 1.00 | ELANE (0.43) | ELANEMEN1KMT2ANPC1POLB | |
| SCHEMBL3275812 | 0.77 | MEN1 (0.41) | ELANEMEN1KMT2ANPC1POLB | |
| SCHEMBL3274811 | 0.72 | MEN1 (0.46) | ELANEMEN1KMT2ANPC1POLB | |
| SCHEMBL3275224 | 0.71 | KMT2A (0.62) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL5273545 | 0.68 | ELANE (0.49) | ELANEMEN1KMT2AHTR2CCYP1A2 | |
| Alanine SCHEMBL3281125 | 0.66 | PTPRA (0.58) | ELANEMEN1KMT2ANPC1POLB | |
| Alanine SCHEMBL3282143 | 0.66 | PTPRA (0.58) | ELANEMEN1KMT2ANPC1POLB | |
| Alanine SCHEMBL3274115 | 0.66 | PTPRA (0.58) | ELANEMEN1KMT2ANPC1POLB | |
| SCHEMBL13338326 | 0.65 | LCK (0.52) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL3666115 | 0.65 | RAB9A (0.46) | MEN1KMT2ANPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625117-B1 | NOVEL PHENOXAZINONE DERIVATIVES AS ENZYME SUBSTRATES AND USE THEREOF AS INDICTOR IN THE DETECTION OF MICROORGANISMS WITH PEPTIDASE ACTIVITY | BIOMERIEUX SA (FR) | 2008-01-09 | — | — | EP | disclosed |