Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260759 | 1.00 | ELANE (0.43) | ELANEDHODHPARP1TNKSTNKS2 | |
| SCHEMBL27638674 | 0.86 | PARP1 (0.36) | DHODHPARP1TNKSTNKS2ALDH1A1 | |
| SCHEMBL5273550 | 0.86 | PARP1 (0.36) | DHODHPARP1TNKSTNKS2ALDH1A1 | |
| SCHEMBL5273021 | 0.81 | MEN1 (0.43) | KDM4EGAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5278217 | 0.80 | ELANE (0.40) | ELANEALDH1A1KDM4EGAAMAPT | |
| SCHEMBL5278206 | 0.80 | ELANE (0.40) | ELANEALDH1A1KDM4EGAAMAPT | |
| SCHEMBL27855864 | 0.78 | GAA (0.56) | ELANEDHODHALDH1A1LMNAHSD17B10 | |
| SCHEMBL5273960 | 0.78 | ACHE (0.57) | ELANE | |
| Hydrochloric Acid SCHEMBL5404005 | 0.77 | ACHE (0.56) | ELANE | |
| Hydrochloric Acid SCHEMBL5414827 | 0.76 | ACHE (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587793-A1 | ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA | BIOMERIEUX (FR) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004069804-A1 | ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA | BIOMERIEUX (FR) | 2004-08-19 | — | — | WO | disclosed |