SCHEMBL5273615

SCHEMBL5273615

C=CC(=O)OOCCOc1cc[c]cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.50
ALDH1A1 P00352 6/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PKM P14618 1/20 0.33
TEAD1 P28347 1/20 0.32
TEAD3 Q99594 1/20 0.32
HTT P42858 2/20 0.32
PARP10 Q53GL7 1/20 0.32
HPGD P15428 1/20 0.31
TSHR P16473 4/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5040437 0.84 THRB (0.71) THRBALDH1A1L3MBTL1MAPTMEN1
SCHEMBL68456 0.84 THRB (0.71) THRBALDH1A1L3MBTL1MAPTMEN1
SCHEMBL8429852 0.80 THRB (0.65) THRBALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL10033663 0.80 THRB (0.65) THRBALDH1A1MAPTMEN1KMT2A
SCHEMBL9362120 0.78 TSHR (0.59) THRBALDH1A1L3MBTL1HTTHPGD
SCHEMBL8663616 0.78 TSHR (0.59) THRBALDH1A1L3MBTL1HTTHPGD
SCHEMBL9357919 0.78 TSHR (0.59) THRBALDH1A1L3MBTL1HTTHPGD
SCHEMBL31571400 0.77 GAA (0.57) THRBALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL10262564 0.76 L3MBTL1 (0.54) THRBALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL23466928 0.76 THRB (0.50) THRBALDH1A1L3MBTL1SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1260278-B1 Method of coating a plastic molding, ultraviolet-curable under coating for metal evaporation, and plastic moldings NIPPON PAINT CO LTD (JP) 2007-10-31 EP disclosed