Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | CYBB | P04839 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272204 | 0.99 | NPC1 (0.45) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| SCHEMBL5579707 | 0.97 | NPC1 (0.43) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| SCHEMBL5277589 | 0.96 | NPC1 (0.44) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| SCHEMBL5279910 | 0.96 | NPC1 (0.44) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| SCHEMBL5272902 | 0.82 | TP53 (0.46) | NPC1RAB9AMAPTKMT2ADRD2 | |
| SCHEMBL5276002 | 0.79 | TP53 (0.46) | NPC1RAB9AMAPTKMT2ATP53 | |
| SCHEMBL5270863 | 0.79 | TP53 (0.46) | NPC1RAB9AMAPTKMT2ADRD2 | |
| SCHEMBL5278464 | 0.79 | PKM (0.45) | NPC1RAB9AMAPTDRD2DRD4 | |
| SCHEMBL5276478 | 0.79 | RAB9A (0.45) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| SCHEMBL5274250 | 0.78 | RAB9A (0.44) | NPC1RAB9AMAPTKMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301033-B2 | PPAR-activating compound | KOWA CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| EP-1857447-A1 | PPAR-ACTIVATING COMPOUND | Kowa Company, Ltd. (JP) | 2007-11-21 | — | — | EP | disclosed |
| US-20060167058-A1 | PPAR-activating compound | KOWA CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167058-A1 | PPAR-activating compound | PPARA, PPARG, PPARD | NPC1 851/4885RAB9A 4288/4885MAPT 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.